Category Archives: News

RECIST disease assessment is effective for targeted treatment as well as classical chemotherapy

Assessing tumour growth and cancer cell proliferation in patients is important both for judging the effectiveness of individual treatment and for the evaluation of therapies in clinical trials. EORTC was among the international organisations that developed RECIST (Response Evaluation Criteria in Solid Tumours), a method of determining whether tumour measurement data can allow the conclusion

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Introducing iRECIST: modified RECIST guideline for immunotherapy

The iRECIST guideline addresses the singularities of immunotherapies, ensuring consistent trial design and interpretation of tumour progression measurements for immune modulators. The guideline takes into account distinctive behaviours linked to these types of therapeutics, such as delayed responses after pseudoprogression, and describes a standard approach to solid tumour measurement and definitions for objective change in tumour

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Assessing RECIST to prepare for new clinical trial models

The RECIST Working Group published their view on the continued relevance of RECIST guidelines and on the challenges to maintain RECIST as a standard for the assessment of tumour burden in clinical trials. “While we recognise that RECIST cannot accommodate all possible protocol specificities, it remains the only general tool that provides harmonisation of tumour

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